Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 12/20 | 0.58 |
| ▸ | GLP1R | P43220 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289643 | 0.93 | FOLH1 (0.55) | FOLH1GLP1R | |
| SCHEMBL12118205 | 0.92 | FOLH1 (0.49) | FOLH1GLP1R | |
| SCHEMBL13557766 | 0.92 | FOLH1 (0.49) | FOLH1GLP1R | |
| SCHEMBL19182223 | 0.89 | FOLH1 (0.65) | FOLH1GLP1R | |
| SCHEMBL15003765 | 0.88 | FOLH1 (0.62) | FOLH1GLP1R | |
| SCHEMBL16276309 | 0.85 | FOLH1 (0.54) | FOLH1GLP1R | |
| SCHEMBL17791821 | 0.85 | FOLH1 (0.54) | FOLH1GLP1R | |
| SCHEMBL10025247 | 0.85 | FOLH1 (0.54) | FOLH1GLP1R | |
| SCHEMBL11986385 | 0.85 | FOLH1 (0.61) | FOLH1GLP1R | |
| SCHEMBL17508865 | 0.85 | FOLH1 (0.61) | FOLH1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170266187-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | PFIZER INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170209374-A1 | METHODS OF CONTROLLING THE MORPHOLOGY OF POLYMERIC NANOPARTICLES | PFIZER (US) | 2017-07-27 | — | — | US | disclosed |
| US-9579386-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160338959-A1 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | PFIZER INC. | 2016-11-24 | — | — | US | disclosed |
| US-9393310-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND THERAPEUTICS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9375481-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND THERAPEUTICS, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140356444-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | BIND THERAPEUTICS, INC. (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140308363-A1 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | BIND THERAPEUTICS, INC. (US) | 2014-10-16 | — | — | US | disclosed |
| US-8663700-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND THERAPEUTICS, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130251757-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2013-09-26 | — | — | US | disclosed |
| US-20130243827-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | BIND THERAPEUTICS, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130236500-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | BIND BIOSCIENCES, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130230567-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | BIND THERAPEUTICS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-8420123-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8318208-B1 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120288541-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2012-11-15 | — | — | US | disclosed |
| US-8206747-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-06-26 | — | — | US | disclosed |
| US-20100068285-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2010-03-18 | — | — | US | disclosed |
| US-20100068286-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308363-A1 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | CD47, LPXN, CD44 | FOLH1 173/4885GLP1R 4560/4885 |
| US-20160338959-A1 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | LDHA, LDHB, LPXN | FOLH1 177/4885GLP1R 4496/4885 |
| US-20100068285-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885GLP1R 4560/4885 |
| US-20130236500-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885GLP1R 4560/4885 |
| US-20140356444-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885GLP1R 4496/4885 |
| US-20130251757-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885GLP1R 4496/4885 |
| US-20120288541-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885GLP1R 4560/4885 |
| US-20130230567-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885GLP1R 4560/4885 |
| US-20170209374-A1 | METHODS OF CONTROLLING THE MORPHOLOGY OF POLYMERIC NANOPARTICLES | CLTB, NCL, CLTA | FOLH1 976/4885GLP1R 4750/4885 |
| US-20100068286-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885GLP1R 4496/4885 |
| US-20170266187-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | MTHFD1, TYMP, FPGS | FOLH1 51/4885GLP1R 4316/4885 |
| US-20130243827-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885GLP1R 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.