Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | ECE1 | P42892 | 12/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15004694 | 0.99 | ACE (0.62) | ACEECE1ERAP2LTA4HALOX15 | |
| SCHEMBL15004693 | 0.92 | ERAP2 (0.67) | ACEECE1ERAP2LTA4H | |
| SCHEMBL30010641 | 0.89 | ACE (0.60) | ACEECE1ERAP2LTA4HALOX15 | |
| SCHEMBL30311059 | 0.88 | ACE (0.64) | ACEECE1ERAP2ALOX15 | |
| SCHEMBL10030546 | 0.87 | ACE (0.71) | ACEECE1ALOX15 | |
| SCHEMBL29816206 | 0.87 | ERAP2 (0.67) | ACEECE1ERAP2 | |
| SCHEMBL30988893 | 0.86 | ACE (0.61) | ACEECE1ERAP2ALOX15 | |
| SCHEMBL30997441 | 0.85 | ACE (0.61) | ACEECE1ERAP2ALOX15 | |
| SCHEMBL8846626 | 0.85 | ACE (0.56) | ACEECE1ERAP2LTA4HALOX15 | |
| SCHEMBL31074338 | 0.85 | ERAP2 (0.67) | ACEECE1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601963-B1 | N-ISOVALEROYL-L-GLUTAMYL-L-TRYPTOPHAN AS AN AGENT INHIBITING THE FORMATION OF ULCERS IN THE STOMACH AND THE DUODENUM | OBSHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU CYTONIR (RU) | 2015-04-22 | — | — | EP | disclosed |
| EP-2601963-A1 | N-ISOVALEROYL-L-GLUTAMYL-L-TRYPTOPHAN AS AN AGENT INHIBITING THE FORMATION OF ULCERS IN THE STOMACH AND THE DUODENUM | Obshestvo S Ogranichennoj Otvetstvennostju "citoNIR" (RU) | 2013-06-12 | — | — | EP | disclosed |