Iodide

Iodide

SCHEMBL15009902

C[N+](C)(C)c1ccc(C=O)cc1.I

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.50
ALDH1A1 P00352 9/20 0.44
TYR P14679 1/20 0.44
CYP2A13 Q16696 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
ALDH1A3 P47895 2/20 0.41
ALDH3A1 P30838 1/20 0.41
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.35
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780476 0.97 CYP2A6 (0.52) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL27942473 0.95 CYP2A6 (0.50) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
Iodide SCHEMBL15412173 0.95 CYP2A6 (0.50) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
Bromide SCHEMBL1885936 0.95 CYP2A6 (0.50) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL6847822 0.85 CYP2A6 (0.41) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL4830852 0.80 ALDH1A1 (0.42) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
Trifluoromethanesulfonic Acid SCHEMBL117933 0.79 CYP2A6 (0.36) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL7051526 0.75 CYP2A6 (0.50) CYP2A6ALDH1A1KDM4ESMN1; SMN2TSHR
SCHEMBL4627437 0.75 ALDH1A1 (0.54) ALDH1A1APOBEC3AAPOBEC3GKDM4E
SCHEMBL5712018 0.75 ALDH1A1 (0.47) CYP2A6ALDH1A1TYRCYP2A13HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9550909-B2 Polyvinyl acetal resin, slurry composition prepared therefrom, ceramic green sheet, and multilayer ceramic capacitor KURARAY CO., LTD. (JP) 2017-01-24 US disclosed
US-9410003-B2 Polyoxyalkylene-modified vinyl acetal polymer, and composition comprising same KURARAY CO., LTD. (JP) 2016-08-09 US disclosed
EP-2607390-B1 POLYVINYL ACETAL RESIN, SLURRY COMPOSITION PREPARED THEREFROM, CERAMIC GREEN SHEET, AND MULTILAYER CERAMIC CAPACITOR KURARAY CO (JP) 2016-06-22 EP disclosed
US-9355777-B2 Slurry composition, ceramic green sheet, and multi layer ceramic capacitor KURARAY CO., LTD. (JP) 2016-05-31 US disclosed
EP-2762463-B1 SLURRY COMPOSITION, CERAMIC GREEN SHEET, AND LAYERED CERAMIC CAPACITOR KURARAY CO (JP) 2016-05-25 EP disclosed
US-20160032131-A1 POLYVINYL ACETAL RESIN, SLURRY COMPOSITION PREPARED THEREFROM, CERAMIC GREEN SHEET, AND MULTILAYER CERAMIC CAPACITOR KURARAY CO., LTD. (JP) 2016-02-04 US disclosed
EP-2679610-B1 POLYOXYALKYLENE-MODIFIED VINYL ACETAL POLYMER, AND COMPOSITION COMPRISING SAME KURARAY CO (JP) 2015-09-16 EP disclosed
US-20140256863-A1 SLURRY COMPOSITION, CERAMIC GREEN SHEET, AND MULTI LAYER CERAMIC CAPACITOR KURARAY CO., LTD. (JP) 2014-09-11 US disclosed
EP-2762463-A1 SLURRY COMPOSITION, CERAMIC GREEN SHEET, AND LAYERED CERAMIC CAPACITOR Kuraray Co., Ltd. (JP) 2014-08-06 EP disclosed
US-20130338306-A1 POLYOXYALKYLENE-MODIFIED VINYL ACETAL POLYMER, AND COMPOSITION COMPRISING SAME KURARAY CO., LTD. (JP) 2013-12-19 US disclosed
EP-2607390-A1 POLYVINYL ACETAL RESIN, SLURRY COMPOSITION PREPARED THEREFROM, CERAMIC GREEN SHEET, AND MULTILAYER CERAMIC CAPACITOR Kuraray Co., Ltd. (JP) 2013-06-26 EP disclosed
US-20130148263-A1 POLYVINYL ACETAL RESIN, SLURRY COMPOSITION PREPARED THEREFROM, CERAMIC GREEN SHEET, AND MULTILAYER CERAMIC CAPACITOR KURARAY CO., LTD (JP) 2013-06-13 US disclosed