Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501349 | 1.00 | MAPT (1.00) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL27753446 | 0.88 | MAPT (0.78) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL10747446 | 0.88 | MAPT (0.78) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL10747444 | 0.88 | MAPT (0.78) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL25225496 | 0.88 | MAPT (0.78) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL25190631 | 0.88 | MAPT (0.78) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL24214416 | 0.86 | MAPT (0.76) | MAPTCYP2C19CYP1B1SMN1; SMN2MEN1 | |
| SCHEMBL24215118 | 0.86 | MAPT (0.76) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL13347975 | 0.86 | MAPT (0.76) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 | |
| SCHEMBL11397615 | 0.86 | MAPT (0.76) | MAPTCYP2C19BCHECYP1B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146216-B | Monoazo and polyazo dyes favorable for health and synthesis method thereof | UNIV ZHENGZHOU | 2013-11-13 | — | — | CN | claimed |
| CN-102146216-A | Monoazo and polyazo dyes favorable for health and synthesis method thereof | UNIV ZHENGZHOU | 2011-08-10 | — | — | CN | claimed |
| CN-102146216-B | Monoazo and polyazo dyes favorable for health and synthesis method thereof | UNIV ZHENGZHOU | 2013-11-13 | — | — | CN | disclosed |
| CN-1984889-B | Organometallic complex, luminous solid, organic EL element and organic EL display | FUJI PHOTO FILM CO LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-102146216-A | Monoazo and polyazo dyes favorable for health and synthesis method thereof | UNIV ZHENGZHOU | 2011-08-10 | — | — | CN | disclosed |
| CN-101357902-B | Method for preparing N- formyl-2H-4chloroquinoline derivate | UNIV ZHEJIANG TECHNOLOGY | 2011-06-29 | — | — | CN | disclosed |
| EP-2291355-A2 | NOVEL TETRAHYDROQUINOLINES AS AROMATASE INHIBITORS | Panjab University (IN) | 2011-03-09 | — | — | EP | disclosed |
| US-20100280070-A1 | NOVEL TETRAHYDROQUINOLINES AS AROMATASE INHIBITORS | AKKINEPALLY RAGHURAM RAO | 2010-11-04 | — | — | US | disclosed |
| WO-2009087684-A2 | NOVEL TETRAHYDROQUINOLINES AS AROMATASE INHIBITORS | PANJAB UNIVERSITY (IN) | 2009-07-16 | — | — | WO | disclosed |
| CN-101357902-A | Method for preparing N- formyl-2H-4chloroquinoline derivate | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-02-04 | — | — | CN | disclosed |
| CN-1329354-C | Fluorescent material, organic electroluminescent element and organic electroluminescent display | FUJITSU LTD (JP) | 2007-08-01 | — | — | CN | disclosed |
| CN-1984889-A | Organometallic complex, luminous solid, organic EL element and organic EL display | FUJI PHOTO FILM CO LTD (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1302087-C | Light-emitting device and aromatic compound | FUJI PHOTO FILM CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
| CN-1609163-A | Fluorescent material, organic electroluminescent element and organic electroluminescent display | FUJITSU LTD (JP) | 2005-04-27 | — | — | CN | disclosed |
| EP-1279671-B1 | Process for enantioselective epoxidation of alpha, beta-unsaturated enones and alpha, beta-unsaturated sulfones catalysed by polyamino acids | BAYER CHEMICALS AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| CN-1527871-A | Light emitting device and aromatic compound | ��ʿ��Ƭ��ʽ���� | 2004-09-08 | — | — | CN | disclosed |
| US-6770766-B2 | QUATERNARY AMMONIUM OR PHOSPHONIUM PHASE TRANSFER CATALYST | BAYER CHEMICALS AG (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20030087401-A1 | Polyamino acid-catalyzed process for the enantioselective epoxidation of alpha,beta-unsaturated enones and alpha,beta-unsaturated sulfones | LANXESS DEUTSCHLAND GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| EP-1279671-A1 | Process for enantioselective epoxidation of alpha, beta-unsaturated enones and alpha, beta-unsaturated sulfones catalysed by polyamino acids | BAYER AG (DE) | 2003-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280070-A1 | NOVEL TETRAHYDROQUINOLINES AS AROMATASE INHIBITORS | CYP19A1, HSD17B11, CYP17A1 | MAPT 4043/4885CYP2C19 16/4885BCHE 258/4885 |
| US-20030087401-A1 | Polyamino acid-catalyzed process for the enantioselective epoxidation of alpha,beta-unsaturated enones and alpha,beta-unsaturated sulfones | COASY, SQLE, ELOVL1 | MAPT 2989/4885CYP2C19 645/4885BCHE 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.