ELOVL1

Very long chain fatty acid elongase 1 · Q9BW60 · ELOVL1 on Sugi Atlas →

6,774 patent compounds predicted against ELOVL1, 3,521 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Iodide Iodide (SCHEMBL2380459) 0.53 10/20
SCHEMBL2864732 SCHEMBL2864732 0.46 10/20
SCHEMBL1356550 SCHEMBL1356550 0.40 10/20
SCHEMBL1944088 SCHEMBL1944088 0.45 9/20
SCHEMBL83628 SCHEMBL83628 0.52 7/20
SCHEMBL83794 SCHEMBL83794 0.52 7/20
SCHEMBL84497 SCHEMBL84497 0.51 7/20
SCHEMBL1259168 SCHEMBL1259168 0.46 7/20
SCHEMBL1062877 SCHEMBL1062877 0.50 6/20
SCHEMBL1505919 SCHEMBL1505919 0.44 6/20
SCHEMBL621931 SCHEMBL621931 0.44 6/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL624262) 0.43 6/20
SCHEMBL1964025 SCHEMBL1964025 0.39 6/20
SCHEMBL623234 SCHEMBL623234 0.51 5/20
SCHEMBL624150 SCHEMBL624150 0.47 5/20
SCHEMBL1063920 SCHEMBL1063920 0.47 5/20
SCHEMBL725497 SCHEMBL725497 0.45 5/20
SCHEMBL1462241 SCHEMBL1462241 0.44 5/20
SCHEMBL2371733 SCHEMBL2371733 0.44 5/20
SCHEMBL2570788 SCHEMBL2570788 0.43 5/20

Clinical trials — most relevant to ELOVL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Omega-3 Fatty Acids on the Human Gene Expression PHASE4COMPLETED
Bezafibrate Trial in CPT2 Deficiency PHASE3UNKNOWN
Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention PHASE2COMPLETED
Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH) PHASE2COMPLETED
Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver PHASE2COMPLETED
Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy PHASE1COMPLETED
The Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism nanACTIVE_NOT_RECRUITING
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction nanUNKNOWN
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders nanRECRUITING
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo nanCOMPLETED
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk nanCOMPLETED
Canola Oil Multicentre Intervention Trial nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Lipid Mediators in Multiple Sclerosis nanCOMPLETED
Effects of Fish Oils on Inflammation and Insulin Resistance nanCOMPLETED
Omegaven Treatment of Parenteral Nutrition (PN) Induced Liver Injury nanCOMPLETED
Serum FFA Desaturase Activity Index in Patients on High Dose Corticosteroids nanUNKNOWN
Stearoyl-CoA Desaturase and Energy Metabolism in Humans nanCOMPLETED
Genotype-related Effects of PUFA nanCOMPLETED
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids. nanCOMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Action of Essential Fatty Acids on the Expression of Antioxidant Genes and Athletic Performance nanCOMPLETED
A Pilot Study of High-Dose Omega-3 (Soloways ™) Polyunsaturated Fatty Acids in Patients with Dyslipidemia Carrying FADS1/FADS2 Variants nanCOMPLETED
Krill Oil Supplementation: Effects on Breast Milk Composition nanCOMPLETED
Fish Oil to Prevent Asthma Exacerbations in Patients With ALOX5 Polymorphisms nanCOMPLETED
Heart & Health Study nanCOMPLETED
Effect of n-3 Polyunsaturated Fatty Acids Supplementation on Human Milk Composition of Lactating Women nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ELOVL1 binder may also engage these)

ProteinNameSimilarity
Q9JLJ5 1.000 Q9JLJ5 →
D4ADY9 0.997 D4ADY9 →
Q9D2Y9 0.993 Q9D2Y9 →
A0JNC4 0.992 A0JNC4 →
A1L3X0 0.990 A1L3X0 →
O35949 0.986 O35949 →
Q9NXB9 0.985 Q9NXB9 →
Q4DHY3 0.982 Q4DHY3 →
Q4D5J7 0.982 Q4D5J7 →
ELOVL3 Very long chain fatty acid elongase 3 0.982 landscape →
Q4DUK4 0.981 Q4DUK4 →
Q9JLJ4 0.980 Q9JLJ4 →
Q32NI8 0.980 Q32NI8 →
Q03574 0.980 Q03574 →
Q9VH58 0.979 Q9VH58 →
B4QVX4 0.979 B4QVX4 →
Q5M8U1 0.978 Q5M8U1 →
Q9VHX7 0.977 Q9VHX7 →
A0A0C5PHQ7 0.976 A0A0C5PHQ7 →
Q54TC9 0.976 Q54TC9 →
Q4QJ85 0.976 Q4QJ85 →
Q9VV87 0.975 Q9VV87 →
D4A612 0.975 D4A612 →
Q9XVQ9 0.975 Q9XVQ9 →
Q57UP6 0.975 Q57UP6 →
P49191 0.974 P49191 →
G5EEE5 0.974 G5EEE5 →
Q20303 0.972 Q20303 →
Q4D321 0.971 Q4D321 →
Q1HRV8 0.971 Q1HRV8 →