Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.62 |
| ▸ | PDE4A | P27815 | 16/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016088 | 0.88 | PDE4D (0.60) | PDE4BPDE4DPDE4APDE4CPDE11A | |
| SCHEMBL74144 | 0.84 | PDE4D (0.64) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL74891 | 0.83 | PDE4D (0.63) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL72686 | 0.83 | PDE4D (0.66) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL73260 | 0.82 | PDE4D (0.64) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL5022238 | 0.81 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL5023369 | 0.79 | PDE4D (0.66) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL4026196 | 0.78 | PDE4D (0.64) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL5016490 | 0.78 | PDE4D (0.63) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL5023283 | 0.78 | PDE4D (0.63) | PDE4BPDE4DPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | claimed |