Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.52 |
| ▸ | PDE4A | P27815 | 16/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016079 | 0.88 | PDE4B (0.62) | PDE4DPDE4BPDE4APDE4CPDE11A | |
| SCHEMBL72937 | 0.85 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL75216 | 0.84 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL75217 | 0.84 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL73200 | 0.84 | PDE4D (0.67) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL73641 | 0.83 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5017912 | 0.82 | PDE4B (0.71) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4026556 | 0.79 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4030622 | 0.79 | PDE4D (0.80) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4029693 | 0.78 | PDE4D (0.79) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | claimed |