Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873773 | 0.90 | KDM4E (0.38) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL73058 | 0.73 | ADORA1 (0.43) | KDM4EP2RX3MAPTSTS | |
| SCHEMBL73073 | 0.72 | ADORA1 (0.42) | KDM4EP2RX3PDE4BMAPTSTS | |
| SCHEMBL3867643 | 0.70 | MAPT (0.38) | LMNAMAPK1PDE4BMAPTALDH1A1 | |
| SCHEMBL72942 | 0.66 | MAPT (0.42) | LMNAKMT2AKDM4EP2RX3MAPT | |
| SCHEMBL73236 | 0.65 | MAPT (0.43) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL19268020 | 0.64 | GPR119 (0.51) | LMNAMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL16843097 | 0.63 | GPR119 (0.43) | LMNAMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL26912289 | 0.62 | KMT2A (0.47) | LMNAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL73099 | 0.61 | PTGDR2 (0.44) | LMNAKMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | claimed |