Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015867 | 0.99 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL29991145 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL29990910 | 0.84 | TDP1 (0.46) | ALDH1A1CYP3A4LMNAMAPK1MEN1 | |
| SCHEMBL9306882 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL23748009 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL9308145 | 0.80 | CNR2 (0.50) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL15016358 | 0.79 | HPGD (0.50) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL31093126 | 0.77 | KMT2A (0.49) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL11370051 | 0.77 | HPGD (0.52) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL15016377 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791145-B1 | ZINC(II) -COMPLEX-COMPOUNDS AS CATALYSTS FOR POLYURETAHNE-COMPOSITIONS | SIKA TECH AG (CH) | 2017-05-03 | — | — | EP | disclosed |
| EP-2791145-A1 | ZINC(II) COMPLEX COMPOUNDS AS CATALYSTS FOR POLYURETHANE COMPOSITIONS | Sika Technology AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087680-A1 | ZINC(II) COMPLEX COMPOUNDS AS CATALYSTS FOR POLYURETHANE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2013-06-20 | — | — | WO | disclosed |
| EP-2604613-A1 | Zinc(II) complexes as catalysts for polyurethane compositions | Sika Technology AG (CH) | 2013-06-19 | — | — | EP | disclosed |