Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691265 | 0.74 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL26725876 | 0.74 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3693305 | 0.72 | SLC6A11 (0.49) | SLC6A3SLC6A2SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL10326678 | 0.70 | KDM4E (0.44) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL10326766 | 0.70 | KDM4E (0.44) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL10326575 | 0.70 | KDM4E (0.44) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL22259841 | 0.69 | KDM4E (0.46) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL22260329 | 0.69 | KDM4E (0.43) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL22259927 | 0.69 | KDM4E (0.43) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 | |
| SCHEMBL25968625 | 0.69 | KDM4E (0.43) | SLC6A3SLC6A2SLC6A4KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791133-A1 | FLUORINATED ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013090836-A1 | FLUORINATED ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |