Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 7/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316552 | 0.91 | HTR4 (0.47) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7333211 | 0.90 | HTR4 (0.46) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8509459 | 0.89 | HTR4 (0.52) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5042500 | 0.88 | HTR4 (0.51) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL14810412 | 0.84 | HTR4 (0.59) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7365194 | 0.82 | HTR4 (0.51) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7361286 | 0.82 | HTR4 (0.44) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5042523 | 0.82 | HTR4 (0.54) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL2944408 | 0.82 | HTR4 (0.50) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL27942442 | 0.81 | SMN1; SMN2 (0.41) | HTR4HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413891-B1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE | SYMED LABS LTD (IN) | 2024-01-03 | — | — | EP | claimed |
| CN-115745929-A | Preparation method of prankari succinate key intermediate | 山东四环药业股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| EP-3413891-A1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE AND ITS INTERMEDIATES | Symed Labs Limited (IN) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137910-A1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE AND ITS INTERMEDIATES | SYMED LABS LIMITED (IN) | 2017-08-17 | — | — | WO | claimed |
| EP-0885190-B1 | N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES | JANSSEN PHARMACEUTICA NV (BE) | 2003-05-07 | — | — | EP | claimed |
| CN-1068881-C | Phenyl-oxo-alkyl-(4-piperidinyl) benzoate derivs. | JANSSEN PHARMACEUTICA NV (BE) | 2001-07-25 | — | — | CN | claimed |
| EP-0784620-B1 | N-SUBSTITUTED PIPERIDINYL BICYCLIC BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1999-12-08 | — | — | EP | claimed |
| EP-0784619-B1 | PHENYL-OXO-ALKYL-(4-PIPERIDINYL)BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1999-03-24 | — | — | EP | claimed |
| CN-1160401-A | Phenyl-oxo-alkyl- (4-piperidinyl) benzoate derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1997-09-24 | — | — | CN | claimed |
| EP-0784619-A1 | PHENYL-OXO-ALKYL-(4-PIPERIDINYL)BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-07-23 | — | — | EP | claimed |
| US-5616738-A | A 7-CARBOXYBENZOFURAN INTERMEDIATE FOR DRUGS HAVING GASTROINTESTINAL MOTILITY STIMULATING PROPERTIES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-04-01 | — | — | US | claimed |
| WO-1996010026-A1 | PHENYL-OXO-ALKYL-(4-PIPERIDINYL)BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-04-04 | — | — | WO | claimed |
| US-4950766-A | Preparation of benzamides useful as antiemetic agents | ERBAMONT, INC. (US) | 1990-08-21 | — | — | US | claimed |
| EP-0314483-A1 | Preparation of benzamides | ERBAMONT, INC. (US) | 1989-05-03 | — | — | EP | claimed |
| EP-4541794-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF | Suzhong Pharmaceutical Group Co., Ltd. (CN) | 2025-04-23 | — | — | EP | disclosed |
| CN-119707895-A | Preparation method of 7-formyl-2, 3-dihydrobenzofuran-4-carbonitrile | 江苏苏中药业研究院有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-4888353-A | Carboxamides useful as antiemetic or antipsychotic agents | ERBAMONT, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0314483-A1 | Preparation of benzamides | ERBAMONT, INC. (US) | 1989-05-03 | — | — | EP | disclosed |
| EP-0234872-A1 | Carboxamides useful as antiemetic or antipsychotic agents | Erbamont Inc. (US) | 1987-09-02 | — | — | EP | disclosed |