Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | BLM | P54132 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | APAF1 | O14727 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020365 | 1.00 | DNM1 (0.61) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15039490 | 1.00 | DNM1 (0.61) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15020045 | 0.94 | DNM1 (0.69) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15020041 | 0.94 | DNM1 (0.69) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15039495 | 0.94 | DNM1 (0.69) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL5509707 | 0.88 | MAPT (0.47) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL5509711 | 0.88 | MAPT (0.47) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15019784 | 0.88 | DNM1 (0.59) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15019783 | 0.88 | DNM1 (0.59) | DNM1RAB9AMAPTBLMMAPK1 | |
| SCHEMBL15039496 | 0.88 | DNM1 (0.59) | DNM1RAB9AMAPTBLMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |