SCHEMBL15021576

SCHEMBL15021576

c1cc(-c2nc(-c3cccc(-n4ccc5ccccc54)c3)nc(-c3cccc(-n4ccc5ccccc54)c3)n2)cc(-n2ccc3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.49
ROCK2 O75116 1/20 0.43
PIM1 P11309 1/20 0.43
PIM3 Q86V86 1/20 0.43
PRKD3 O94806 1/20 0.40
PRKCG P05129 1/20 0.40
PRKCB P05771 1/20 0.40
PRKCA P17252 1/20 0.40
PRKACA P17612 1/20 0.40
PRKACG P22612 1/20 0.40
PRKACB P22694 1/20 0.40
PRKCH P24723 1/20 0.40
PRKCI P41743 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCZ Q05513 1/20 0.40
PRKCD Q05655 1/20 0.40
PRKD1 Q15139 1/20 0.40
MGLL Q99685 1/20 0.40
CDC7 O00311 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22649091 0.97 BIRC5 (0.46) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL20180534 0.94 BIRC5 (0.44) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL15021166 0.92 BIRC5 (0.45) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL21462930 0.90 BIRC5 (0.50) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL27867747 0.86 BIRC5 (0.43) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL24886410 0.86 BIRC5 (0.51) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL10112723 0.86 BIRC5 (0.51) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL15021513 0.86 BIRC5 (0.53) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL11910172 0.84 BIRC5 (0.60) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL27931150 0.83 CYP1A2 (0.49) BIRC5ROCK2PIM1PIM3CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115119-B2 Electron transport material and organic light emitting device AU OPTRONICS CORPORATION (TW) 2015-08-25 US disclosed
US-9115119-B2 Electron transport material and organic light emitting device AU OPTRONICS CORPORATION (TW) 2015-08-25 US disclosed
US-9115119-B2 Electron transport material and organic light emitting device AU OPTRONICS CORPORATION (TW) 2015-08-25 US disclosed
CN-102593374-B Electron transport material and organic light-emitting device AU OPTRONICS CORP 2014-09-03 CN disclosed
US-20130153863-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE AU OPTRONICS CORPORATION (TW) 2013-06-20 US disclosed
US-20130153863-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE AU OPTRONICS CORPORATION (TW) 2013-06-20 US disclosed
US-20130153863-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE AU OPTRONICS CORPORATION (TW) 2013-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130153863-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE SLC18A1, SLC1A2, SLC29A1 BIRC5 2913/4885ROCK2 4601/4885PIM1 2030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.