SCHEMBL1502161

SCHEMBL1502161

[SiH3]O[SiH2]CCCOCC1CO1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPK1 P28482 1/20 0.37
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8512776 0.89 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7941221 0.86 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17727830 0.85 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3959552 0.84 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL150450 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5522882 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7629065 0.79 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3797904 0.79 SMN1; SMN2 (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7215607 0.79 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8002488 0.79 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118029011-A PLA-PHA parallel composite elastic fiber and preparation method thereof 苏州大学 2024-05-14 CN claimed
CN-117802626-B PHA-PLA sheath-core composite fiber and preparation method thereof 苏州大学 2024-05-10 CN claimed
CN-117802626-A PHA-PLA sheath-core composite fiber and preparation method thereof 苏州大学 2024-04-02 CN claimed
CN-114044909-B Siloxane quaternary ammonium salt antibacterial softening agent and preparation method thereof 南昌良良实业有限公司 2022-11-29 CN claimed
CN-115232353-A Low-odor scratch-resistant polypropylene composition, expanded beads, preparation method of expanded beads and polypropylene expanded bead forming body 中国石油化工股份有限公司 2022-10-25 CN claimed
CN-112522955-B Preparation method of environmentally-friendly and durable fabric antistatic agent 浙江轩日科技股份有限公司 2021-11-05 CN claimed
CN-112522955-A Preparation method of environmentally-friendly and durable fabric antistatic agent 广西漫迪丽生物科技有限公司 2021-03-19 CN claimed
EP-0383835-A1 SURFACE-ACTIVE POLYSILOXANES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-08-29 EP claimed
US-4910015-A Crosslinked polymer of polyethylene oxide and glycidoxypropylsiloxane MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-03-20 US claimed
US-4906465-A Antithrombogenic devices containing polysiloxanes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-03-06 US claimed
WO-1989003851-A1 SURFACE-ACTIVE POLYSILOXANES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-05-05 WO claimed
CN-121914553-A Water-based organosilicon waterproofing agent and preparation method thereof 南京新义合成科技有限公司 2026-04-24 CN disclosed
US-12422750-B2 Method of manufacturing cured film, photocurable resin composition, method of manufacturing laminate, and method of manufacturing semiconductor device FUJIFILM CORPORATION (JP) 2025-09-23 US disclosed
US-20250264801-A1 RESIN COMPOSITION, CURED SUBSTANCE, LAMINATE, MANUFACTURING METHOD FOR CURED SUBSTANCE, MANUFACTURING METHOD FOR LAMINATE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2025-08-21 US disclosed
EP-4596608-A1 RESIN COMPOSITION, CURED PRODUCT, LAMINATE, METHOD FOR PRODUCING CURED PRODUCT, METHOD FOR PRODUCING LAMINATE, METHOD FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJIFILM Corporation (JP) 2025-08-06 EP disclosed
US-4910015-A Crosslinked polymer of polyethylene oxide and glycidoxypropylsiloxane MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-03-20 US disclosed
US-4906465-A Antithrombogenic devices containing polysiloxanes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-03-06 US disclosed
US-4906465-A Antithrombogenic devices containing polysiloxanes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-03-06 US disclosed
WO-1989003851-A1 SURFACE-ACTIVE POLYSILOXANES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-05-05 WO disclosed
WO-1989003851-A1 SURFACE-ACTIVE POLYSILOXANES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-05-05 WO disclosed