⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858153 | 0.97 | — | — | |
| SCHEMBL28044628 | 0.82 | — | — | |
| SCHEMBL8198866 | 0.80 | CYP4F2 (0.42) | — | |
| SCHEMBL8526781 | 0.80 | CYP4F2 (0.42) | — | |
| SCHEMBL5340873 | 0.79 | — | — | |
| SCHEMBL12598766 | 0.78 | CYP4F2 (0.36) | — | |
| SCHEMBL477872 | 0.78 | — | — | |
| SCHEMBL2882132 | 0.76 | CYP4F2 (0.39) | — | |
| SCHEMBL24685351 | 0.75 | LPAR1 (0.31) | — | |
| SCHEMBL6448246 | 0.75 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11534434-B2 | Xanomeline derivatives and methods for treating neurological disorders | Karuna Therapeutics, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| US-20210145810-A1 | XANOMELINE DERIVATIVES AND METHODS FOR TREATING NEUROLOGICAL DISORDERS | Karuna Therapeutics, Inc. | 2021-05-20 | — | — | US | disclosed |
| WO-2021097427-A1 | XANOMELINE DERIVATIVES AND METHODS FOR TREATING NEUROLOGICAL DISORDERS | Karuna Therapeutics, Inc. (US) | 2021-05-20 | — | — | WO | disclosed |
| US-20210127678-A1 | ESTERS OF HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND THEIR USE | ISAGRO S.P.A. (IT) | 2021-05-06 | — | — | US | disclosed |
| EP-3436433-B1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. | ISAGRO SPA (IT) | 2020-01-22 | — | — | EP | disclosed |
| US-10464893-B2 | Derivatives of pyrrole-2,5-diones having a fungicidal activity, their agronomical compositions and use thereof | ISAGRO S.P.A (IT) | 2019-11-05 | — | — | US | disclosed |
| US-20190106388-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2019-04-11 | — | — | US | disclosed |
| EP-3436433-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. | ISAGRO S.p.A. (IT) | 2019-02-06 | — | — | EP | disclosed |
| WO-2017168368-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. | ISAGRO S.P.A. (IT) | 2017-10-05 | — | — | WO | disclosed |
| US-9040457-B2 | Phenylamidines having a high fungicidal activity and use thereof | ISAGRO S.P.A. (IT) | 2015-05-26 | — | — | US | disclosed |
| US-20130157851-A1 | PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF | ISAGRO S.P.A. (IT) | 2013-06-20 | — | — | US | disclosed |