Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438002 | 0.97 | TDP1 (0.46) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL15297874 | 0.97 | TDP1 (0.46) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL20437994 | 0.97 | TDP1 (0.46) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL20438000 | 0.97 | TDP1 (0.46) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL12506171 | 0.94 | CYP4F2 (0.39) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL27902784 | 0.91 | TDP1 (0.42) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL5184081 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL1659019 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL1658296 | 0.89 | SMN1; SMN2 (0.55) | SMN1; SMN2TDP1FFAR1CPT2CYP4F2 | |
| SCHEMBL1657812 | 0.89 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143599-A1 | Process for preparing monoesters | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143599-A1 | Process for preparing monoesters | ADSL, COASY, AGPS | SMN1; SMN2 3677/4885TDP1 2541/4885FFAR1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.