Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601662 | 0.92 | SIGMAR1 (0.40) | C5AR1SLC6A9SIGMAR1BCHESLC2A1 | |
| SCHEMBL15023492 | 0.88 | SIGMAR1 (0.44) | C5AR1SLC6A9SIGMAR1BCHES1PR1 | |
| SCHEMBL18601655 | 0.85 | C5AR1 (0.39) | C5AR1SLC6A9SIGMAR1BCHESLC2A1 | |
| SCHEMBL18601664 | 0.84 | C5AR1 (0.40) | C5AR1SLC6A9FAAHCES1 | |
| SCHEMBL1979687 | 0.83 | SIGMAR1 (0.41) | C5AR1SLC6A9SIGMAR1BCHESLC2A1 | |
| SCHEMBL15023203 | 0.83 | S1PR1 (0.39) | C5AR1SLC6A9SIGMAR1BCHESLC2A1 | |
| SCHEMBL1979555 | 0.83 | S1PR2 (0.52) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1982037 | 0.83 | S1PR1 (0.39) | C5AR1SLC6A9SLC2A1S1PR1S1PR3 | |
| SCHEMBL1980123 | 0.82 | C5AR1 (0.41) | C5AR1SLC6A9FAAHCES1 | |
| SCHEMBL15042475 | 0.82 | S1PR1 (0.38) | C5AR1SLC6A9SIGMAR1BCHESLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741875-B2 | Compounds as receptor modulators with therapeutic utility | ALLERGAN, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130157982-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157982-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | S1PR1, S1PR3, S1PR2 | C5AR1 420/4885SLC6A9 3922/4885SIGMAR1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.