Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of O-Xylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL30374736 | 1.00 | TSHR (0.62) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL30445238 | 1.00 | TSHR (0.62) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL17255245 | 1.00 | TSHR (0.62) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL29061119 | 1.00 | TSHR (0.62) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL29498826 | 1.00 | TSHR (0.62) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL27889177 | 0.97 | TSHR (0.59) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL29116664 | 0.97 | TSHR (0.59) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL27899695 | 0.91 | TSHR (0.59) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL29211931 | 0.89 | TSHR (0.55) | TSHRACHEACP3HPGDCA2 | |
| O-Xylene SCHEMBL2413714 | 0.88 | TSHR (0.56) | TSHRACHEACP3HPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120149526-A | Low-temperature-resistant incombustible polymer lithium battery electrolyte and preparation method thereof | 中国科学院长春应用化学研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-119592293-B | High-frequency adhesive for flexible copper-clad plate and preparation method thereof | 湖北恒驰电子科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119592293-A | High-frequency adhesive for flexible copper-clad plate and preparation method thereof | 湖北恒驰电子科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119463536-A | Carbon material, preparation method, water-based conductive coating and carbon-coated aluminum foil | 广州慧谷新材料科技股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-117550962-B | Preparation method of 5, 6-dimethyl-5-hepten-2-one | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119410141-A | Polyamide molding composition and preparation method and application thereof | 上海金发科技发展有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-119371392-A | Method for preparing naphthopyran compounds without transition metal catalysis | 广西民族大学 | 2025-01-28 | — | — | CN | claimed |
| CN-119144208-A | Protective coating capable of turning over templates and protective treatment method | 中国十七冶集团有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-118955021-A | Gangue curing agent and preparation method thereof | 中煤西安设计工程有限责任公司 | 2024-11-15 | — | — | CN | claimed |
| CN-110052328-B | Special conveyor of municipal refuse | 广西大自然再生资源有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-111363203-A | Functional color change auxiliary agent composition and preparation method thereof | 四川大学 | 2020-07-03 | — | — | CN | claimed |
| CN-111320799-A | Auxiliary agent composition for color change in light-colored base polymer and preparation method thereof | 四川大学 | 2020-06-23 | — | — | CN | claimed |
| CN-110669472-A | Transparent flame-retardant silicone sealant | 重庆天旗实业有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-109796742-A | Polycarbonate compositions and sulfonate and phosphorus-containing compound are in the application for reducing polycarbonate smoke and heat release | 金发科技股份有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-109777073-A | Polycarbonate compositions and sulfonate and phosphorus-containing compound are in the application for reducing polycarbonate smoke and heat release | 金发科技股份有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109694568-A | A kind of High glow wire halogen-free flame retardant polyamide compound and the preparation method and application thereof | 广州市寅源新材料科技有限公司 | 2019-04-30 | — | — | CN | claimed |
| CN-109385050-A | A kind of low-smoke low-toxicity copolymerized polyester elastic body composition | 深圳市百事达先进材料有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-106816596-A | A kind of preparation method of modified trielement composite material | 江苏乐能电池股份有限公司 | 2017-06-09 | — | — | CN | claimed |
| CN-103570759-B | Continuous alkali washing method of resorcinol bis (di-2, 6-dimethylphenyl phosphate) | PETROCHINA COMPANY LIMITED (CN) | 2015-11-18 | — | — | CN | claimed |
| WO-2011025961-A2 | THERMOSETTING RESIN COMPOSITIONS AND ARTICLES | PARK ELECTROCHEMICAL CORPORATION (US) | 2011-03-03 | — | — | WO | claimed |