SCHEMBL15024869

SCHEMBL15024869

O=C(O)C=CC(=O)OCN1CCCC1=O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.54
TSHR P16473 2/20 0.44
KMT2A Q03164 2/20 0.43
HCAR2 Q8TDS4 7/20 0.41
HTT P42858 1/20 0.39
PIK3CD O00329 1/20 0.38
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
INMT O95050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12515511 0.94 BLM (0.51) BLMTSHRKMT2AHCAR2HTT
SCHEMBL11316348 0.94 TSHR (0.49) BLMTSHRKMT2AHTTPIK3CD
SCHEMBL17695760 0.86 TSHR (0.42) BLMTSHRKMT2AHCAR2HTT
SCHEMBL15024710 0.86 TSHR (0.42) BLMTSHRKMT2AHTTPIK3CD
SCHEMBL402937 0.85 BLM (0.51) BLMTSHRKMT2AHCAR2HTT
SCHEMBL402938 0.85 BLM (0.51) BLMTSHRKMT2AHCAR2HTT
SCHEMBL12655903 0.85 BLM (0.51) BLMTSHRKMT2AHCAR2HTT
SCHEMBL12655666 0.82 BLM (0.49) BLMTSHRKMT2AHCAR2ALDH1A1
SCHEMBL7629454 0.81 TSHR (0.46) BLMTSHRKMT2AHTTPIK3CD
SCHEMBL15024709 0.81 KMT2A (0.40) BLMTSHRKMT2APIK3CDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9512325-B2 Compositions comprising a reactive monomer and uses thereof ISP INVESTMENTS LLC (US) 2016-12-06 US disclosed
US-9512325-B2 Compositions comprising a reactive monomer and uses thereof ISP INVESTMENTS LLC (US) 2016-12-06 US disclosed
EP-2501728-B1 ALKYL LACTAM ESTER POLYMERS, AND USES THEREOF ISP INVESTMENTS INC (US) 2015-01-07 EP disclosed
US-20130150481-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF HERCULES LLC 2013-06-13 US disclosed
US-20130150481-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF HERCULES LLC 2013-06-13 US disclosed