Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515479 | 0.94 | KMT2A (0.43) | TSHRKMT2APIK3CDBLMHTT | |
| SCHEMBL11316348 | 0.86 | TSHR (0.49) | TSHRKMT2APIK3CDBLMHTT | |
| SCHEMBL437536 | 0.84 | POLB (0.45) | TSHRKMT2APIK3CDBLMALDH1A1 | |
| SCHEMBL6655502 | 0.81 | TSHR (0.47) | TSHRKMT2AALDH1A1TP53HIF1A | |
| SCHEMBL15024869 | 0.81 | BLM (0.54) | TSHRKMT2APIK3CDBLMHTT | |
| SCHEMBL30263675 | 0.80 | TSHR (0.50) | TSHRKMT2AALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL20471367 | 0.80 | POLB (0.45) | TSHRKMT2ABLMHTTALDH1A1 | |
| SCHEMBL17695760 | 0.80 | TSHR (0.42) | TSHRKMT2APIK3CDBLMHTT | |
| SCHEMBL15024710 | 0.80 | TSHR (0.42) | TSHRKMT2APIK3CDBLMHTT | |
| SCHEMBL19146018 | 0.79 | TSHR (0.53) | TSHRKMT2AALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250073018-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-03-06 | — | — | US | claimed |
| WO-2025045458-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-03-06 | — | — | WO | claimed |
| CN-114478916-B | N-vinyl pyrrolidone-methacrylate random copolymer and preparation method thereof | 辽宁大学 | 2023-09-15 | — | — | CN | claimed |
| US-20250145562-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-05-08 | — | — | US | disclosed |
| US-20250073018-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2025-03-06 | — | — | US | disclosed |
| WO-2025045458-A1 | OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-03-06 | — | — | WO | disclosed |
| US-10844154-B2 | Proliferous copolymers comprising lactamic moieties | ISP INVESTMENTS LLC (US) | 2020-11-24 | — | — | US | disclosed |
| WO-2018017408-A1 | A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2018-01-25 | — | — | WO | disclosed |
| WO-2018017570-A1 | A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2018-01-25 | — | — | WO | disclosed |
| CN-104185670-A | New aqueous fracturing fluid composition and fracturing method implementing the fluid | SPCM SA | 2014-12-03 | — | — | CN | disclosed |
| CN-101849209-B | Composition for forming top anti-reflection film and pattern forming method using the same | AZ ELECTRONIC MATERIALS JAPAN | 2012-11-28 | — | — | CN | disclosed |
| CN-102300634-A | Method for controlling water evaporation | — | 2011-12-28 | — | — | CN | disclosed |
| CN-101849209-A | Composition for forming top anti-reflection film and pattern forming method using the same | AZ ELECTRONIC MATERIALS JAPAN | 2010-09-29 | — | — | CN | disclosed |
| CN-101616658-A | Polysiloxane block copolymers | CIBA HOLDING INC | 2009-12-30 | — | — | CN | disclosed |
| US-6465588-B1 | PARTICULARLY SUITABLE FOR FOLDABLE INTRAOCULAR LENS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| EP-0869138-B1 | NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-6132462-A | HYDROXYALKYL (ALKYL)ACRYLATE; PYRROLIDONE-CONTAINING ACRYLIC ESTER, AMIDE, OR IMIDE; AND A LOWER ALKYL (ALKYL)ACRYLATE TERPOLYMER; FOLDABLE LENSE HAVING GIVEN REFRACTIVE INDEX, RECOVERY SPEED FROM FOLD STATE AND TENSILE STRENGTH | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-1026182-A1 | FOUR COMPONENT COPOLYMER AND THE OCULAR LENS MADE THEREOF | SANTEN PHARMACEUTICAL CO., LTD (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0869138-A1 | NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145562-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES | CRY1, NFXL1, ZYX | TSHR 3668/4885KMT2A 2325/4885PIK3CD 4542/4885 |
| US-10844154-B2 | Proliferous copolymers comprising lactamic moieties | PCNA, MKI67, CCNA1 | TSHR 4126/4885KMT2A 1923/4885PIK3CD 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.