SCHEMBL15024903

SCHEMBL15024903

c1ccc(-n2c3ccccc3c3c4cc(-n5c6ccccc6c6ccccc65)ccc4n(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c32)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ATM Q13315 1/20 0.56
JAK2 O60674 1/20 0.38
JAK3 P52333 1/20 0.38
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPN1 P18031 2/20 0.35
MAPK8 P45983 2/20 0.34
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
MAPK9 P45984 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15113987 0.97 L3MBTL1 (0.56) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17689957 0.94 L3MBTL1 (0.60) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16482580 0.94 L3MBTL1 (0.60) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL15024883 0.94 L3MBTL1 (0.64) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16276631 0.94 L3MBTL1 (0.53) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL15114067 0.92 L3MBTL1 (0.57) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL15024888 0.90 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL15113967 0.90 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL15113964 0.90 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL15113997 0.89 L3MBTL1 (0.67) L3MBTL1KDM4EATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617724-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-07-05 EP disclosed
US-8766248-B2 Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
US-8766248-B2 Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
EP-2617724-A1 NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-07-24 EP disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed