SCHEMBL15025871

SCHEMBL15025871

Cc1ccc(-c2nc(-c3cc(C)c(-c4ccc(C)cc4)c(C)c3)cc(-c3cc(C)c(-c4ccc(C)cc4)c(C)c3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 6/20 0.45
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ADORA1 P30542 2/20 0.42
AGTR1 P30556 1/20 0.41
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP1B1 Q16678 1/20 0.40
NTSR1 P30989 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
EGFR P00533 1/20 0.38
KDR P35968 1/20 0.38
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15025908 0.91 ADORA3 (0.45) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL15025703 0.91 ADORA3 (0.47) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL15025992 0.88 ADORA3 (0.40) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL15025688 0.84 ADORA3 (0.40) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL11976557 0.83 MEN1 (0.59) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL12622364 0.82 PDGFRB (0.40) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL12306173 0.81 MEN1 (0.57) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL12628206 0.81 MEN1 (0.57) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL15025988 0.81 MEN1 (0.57) ADORA3MEN1KMT2AALDH1A1MAPT
SCHEMBL12306174 0.81 MEN1 (0.57) ADORA3MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed