SCHEMBL15025874

SCHEMBL15025874

Cc1ccc(-c2cc(-c3cnc(C)nc3)cc(-c3cnc(C)nc3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ADORA3 P0DMS8 4/20 0.44
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
AGTR1 P30556 1/20 0.40
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
CYP2C19 P33261 1/20 0.39
METAP2 P50579 1/20 0.39
METAP1 P53582 1/20 0.39
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
CTRC Q99895 1/20 0.39
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15025910 0.94 MEN1 (0.49) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL11976568 0.83 ADORA3 (0.45) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL11976563 0.83 MEN1 (0.49) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL13173500 0.82 KMT2A (0.63) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL15025704 0.81 MEN1 (0.47) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL17051540 0.80 CCR1 (0.44) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL15025991 0.80 ADORA3 (0.46) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL14804381 0.80 ADORA3 (0.50) MEN1KMT2AADORA3MAPTKDM4E
SCHEMBL10000246 0.80 NPSR1 (0.48) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL10000245 0.80 NPSR1 (0.48) MEN1KMT2AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed