Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.71 |
| ▸ | BACE1 | P56817 | 16/20 | 0.71 |
| ▸ | BCHE | P06276 | 14/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367985 | 0.84 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11100154 | 0.83 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL3594567 | 0.83 | ACHE (0.71) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15006724 | 0.82 | ACHE (0.70) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15006925 | 0.82 | ACHE (0.70) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11100747 | 0.82 | ACHE (0.70) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4205093 | 0.82 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL28829907 | 0.81 | ACHE (0.65) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4214710 | 0.81 | ACHE (0.47) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL15025472 | 0.80 | ACHE (0.67) | ACHEBACE1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150341-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150341-A1 | NOVEL COMPOUNDS | GRM5, GRM1, GRIK5 | ACHE 243/4885BACE1 233/4885BCHE 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.