SCHEMBL150274

SCHEMBL150274

O=c1ccn([C@@]2(Br)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 12/20 0.59
POLA1 P09884 1/20 0.56
P2RY2 P41231 12/20 0.54
P2RY4 P51582 8/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986335 0.90 P2RY6 (0.50) P2RY6POLA1P2RY2P2RY4
Triphosphate SCHEMBL27589399 0.89 P2RY6 (0.52) P2RY6POLA1P2RY2P2RY4
SCHEMBL1129337 0.88 P2RY6 (0.60) P2RY6POLA1P2RY2P2RY4
SCHEMBL8441087 0.87 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL26676224 0.87 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL7745802 0.87 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL28293726 0.86 P2RY6 (0.58) P2RY6POLA1P2RY2P2RY4
SCHEMBL1129233 0.85 P2RY6 (0.62) P2RY6POLA1P2RY2P2RY4
SCHEMBL30225451 0.85 P2RY6 (0.58) P2RY6POLA1P2RY2P2RY4
SCHEMBL8436036 0.85 P2RY6 (0.58) P2RY6POLA1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7087375-B1 Method for determining the mechanism of HIV RT inhibitors VIRCO, N.V. (BE) 2006-08-08 US claimed
CN-117377774-A Method for sensitive analyte detection and kit therefor 卡维迪有限公司 2024-01-09 CN disclosed
CN-109868309-B Single-stranded DNA amplification method based on universal base substitution insertion 苏州恩可医药科技有限公司 2022-11-11 CN disclosed
CN-109852727-B HBV-cccDNA detection method and kit based on universal base substitution insertion 苏州恩可医药科技有限公司 2022-10-11 CN disclosed
EP-1583843-B1 SINGLE PRIMER WHOLE GENOME AMPLIFICATION QIAGEN GMBH (DE) 2018-07-18 EP disclosed
EP-3294326-A1 PRIME-BOOST REGIMENS INVOLVING ADMINISTRATION OF AT LEAST ONE MRNA CONSTRUCT CureVac AG (DE) 2018-03-21 EP disclosed
US-9593366-B2 Individually synthesized primers to be used in whole genome amplification QIAGEN GAITHERSBURG, INC. (US) 2017-03-14 US disclosed
EP-1444355-B1 NUCLEIC ACID AMPLIFICATION QIAGEN GMBH (DE) 2017-01-18 EP disclosed
WO-2016184822-A1 PRIME-BOOST REGIMENS INVOLVING ADMINISTRATION OF AT LEAST ONE MRNA CONSTRUCT CUREVAC AG (DE) 2016-11-24 WO disclosed
US-9487823-B2 Nucleic acid amplification QIAGEN GMBH (DE) 2016-11-08 US disclosed
WO-1997011198-A1 RAPID AND SENSITIVE ASSAYS FOR DETECTING AND DISTINGUISHING BETWEEN PROCESSIVE AND NON-PROCESSIVE TELOMERASE ACTIVITIES CTRC RESEARCH FOUNDATION (US) 1997-03-27 WO disclosed
WO-1997011198-A1 RAPID AND SENSITIVE ASSAYS FOR DETECTING AND DISTINGUISHING BETWEEN PROCESSIVE AND NON-PROCESSIVE TELOMERASE ACTIVITIES CTRC RESEARCH FOUNDATION (US) 1997-03-27 WO disclosed
WO-1997008345-A1 METHODS FOR LABELING DNA ENDS WITH HALOGENATED NUCLEOTIDES AND DETECTING SAME WITH ANTIBODIES NEW YORK MEDICAL COLLEGE (US) 1997-03-06 WO disclosed
EP-0686202-A1 PRENATAL SCREENING BRANDEIS UNIVERSITY (US) 1995-12-13 EP disclosed
WO-1994018344-A1 PRENATAL SCREENING BRANDEIS UNIVERSITY (US) 1994-08-18 WO disclosed
EP-0417161-A4 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS 1992-08-12 EP disclosed
EP-0417161-A1 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS APPLIED BIOSYSTEMS, INC. (US) 1991-03-20 EP disclosed
WO-1990001562-A1 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS APPLIED BIOSYSTEMS, INC. (US) 1990-02-22 WO disclosed
WO-1985002415-A1 NON RADIOACTIVE PROBE AND PROCESS FOR THE CHARACTERIZATION OF A DTERMINED NUCLEOTIDE SEQUENCE AND MEANS FOR THE PRODUCTION OF SAID NON RADIOACTIVE PROBE INSTITUT PASTEUR (FR) 1985-06-06 WO disclosed
EP-0143059-A1 Non-radioactive probe and process for the characterization of a particular nucleotide sequence, and means for the production of this non-radioactive probe INSTITUT PASTEUR (FR) 1985-05-29 EP disclosed