SCHEMBL30225451

SCHEMBL30225451

O=C[C@]1(n2ccc(=O)[nH]c2=O)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 13/20 0.58
POLA1 P09884 1/20 0.54
P2RY2 P41231 11/20 0.53
P2RY4 P51582 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129337 0.86 P2RY6 (0.60) P2RY6POLA1P2RY2P2RY4
SCHEMBL26676224 0.85 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL150274 0.85 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL8441087 0.85 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL7745802 0.85 P2RY6 (0.59) P2RY6POLA1P2RY2P2RY4
SCHEMBL28293726 0.84 P2RY6 (0.58) P2RY6POLA1P2RY2P2RY4
SCHEMBL1129233 0.84 P2RY6 (0.62) P2RY6POLA1P2RY2P2RY4
SCHEMBL8436036 0.84 P2RY6 (0.58) P2RY6POLA1P2RY2P2RY4
SCHEMBL4619794 0.83 P2RY6 (0.55) P2RY6POLA1P2RY2P2RY4
SCHEMBL18797120 0.83 P2RY6 (0.55) P2RY6POLA1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4381093-A1 METHODS OF DETERMINING THE NUMBER OF COPIES OR SEQUENCE OF ONE OR MORE RNA MOLECULES Basic Genomics AB (SE) 2024-06-12 EP disclosed
WO-2023012065-A1 METHODS OF DETERMINING THE NUMBER OF COPIES OR SEQUENCE OF ONE OR MORE RNA MOLECULES BASIC GENOMICS AB (SE) 2023-02-09 WO disclosed