Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028109 | 0.83 | GBA1 (0.49) | MEN1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL15028120 | 0.82 | CDK5 (0.33) | — | |
| SCHEMBL15028075 | 0.82 | CDK5 (0.33) | — | |
| SCHEMBL15028189 | 0.73 | MEN1 (0.32) | MEN1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL21253842 | 0.67 | CDK5 (0.41) | — | |
| SCHEMBL15028229 | 0.65 | CCNA2 (0.35) | ALDH1A1CYP2C9 | |
| SCHEMBL20895831 | 0.63 | CCNE2 (0.48) | MEN1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL20895830 | 0.63 | CCNE2 (0.48) | MEN1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2317472 | 0.63 | CCNE2 (0.48) | MEN1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2317462 | 0.63 | CCNE2 (0.48) | MEN1USP2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086436-A1 | COMPOSITIONS AND METHODS FOR ENHANCED GENERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2013-06-13 | — | — | WO | disclosed |