Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230975 | 0.95 | TSHR (0.60) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL16380606 | 0.94 | TSHR (0.53) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL494373 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL495321 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL494361 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL496150 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL494159 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL495716 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL494538 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL494744 | 0.94 | DGKA (0.61) | TSHRCYP3A4ATMTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086322-A1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-06-13 | — | — | WO | disclosed |