Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012447 | 1.00 | ESR1 (0.45) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL9995690 | 0.93 | ESR1 (0.43) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL9995717 | 0.93 | ESR1 (0.43) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012577 | 0.93 | ESR1 (0.48) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15028676 | 0.93 | ESR1 (0.48) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012360 | 0.90 | ESR1 (0.40) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012515 | 0.89 | ESR1 (0.41) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012970 | 0.89 | ESR1 (0.41) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012694 | 0.89 | ESR1 (0.46) | ESR1ESR2MAOAMAOBPRKCI | |
| SCHEMBL15012953 | 0.89 | ESR1 (0.46) | ESR1ESR2MAOAMAOBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-19 | — | — | US | disclosed |
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-19 | — | — | US | disclosed |
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-19 | — | — | US | disclosed |
| WO-2013083568-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, AND USE THEREOF TO PRODUCE DRUGS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | CYP19A1, SHBG, ESR2 | ESR1 4/4885ESR2 3/4885MAOA 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.