Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.47 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9995710 | 0.94 | MAPK14 (0.47) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL16567972 | 0.92 | CYP24A1 (0.51) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL15263331 | 0.90 | CYP24A1 (0.51) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL15263188 | 0.87 | MAPK14 (0.49) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL12698728 | 0.86 | CYP24A1 (0.46) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL9995684 | 0.85 | SLC6A2 (0.49) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL15012685 | 0.83 | CYP24A1 (0.44) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL9995721 | 0.82 | CYP24A1 (0.47) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL9995652 | 0.82 | CYP24A1 (0.47) | CYP24A1CYP27A1CYP26A1CYP19A1MAPK14 | |
| SCHEMBL26187133 | 0.82 | CYP24A1 (0.42) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-19 | — | — | US | disclosed |
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-19 | — | — | US | disclosed |
| WO-2013083568-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, AND USE THEREOF TO PRODUCE DRUGS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080438-A1 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments | CYP19A1, SHBG, ESR2 | CYP24A1 32/4885CYP27A1 187/4885CYP26A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.