Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.54 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25561987 | 0.85 | EPHX1 (0.46) | EPHX1DPP4ALDH1A1MAPTNPSR1 | |
| SCHEMBL15029007 | 0.82 | EPHX2 (0.45) | EPHX1DPP4ALDH1A1EPHX2DPP7 | |
| SCHEMBL15029131 | 0.82 | GRIN2D (0.40) | EPHX1DPP4EPHX2DPP7FAP | |
| SCHEMBL18425801 | 0.72 | GRIN2D (0.59) | EPHX1DPP4EPHX2GRIN2DGRIN3B | |
| SCHEMBL19840693 | 0.72 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL12196135 | 0.71 | EPHX1 (1.00) | EPHX1ALDH1A1MAPTNPSR1EPHX2 | |
| SCHEMBL3188537 | 0.71 | GRIN2D (0.50) | EPHX1DPP4EPHX2DPP7GRIN2D | |
| SCHEMBL1678053 | 0.70 | GRIN2D (0.39) | EPHX1DPP4ALDH1A1MAPTNPSR1 | |
| SCHEMBL15315878 | 0.69 | L3MBTL1 (0.47) | EPHX1DPP4ALDH1A1MAPTNPSR1 | |
| SCHEMBL14503349 | 0.68 | EPHX2 (0.43) | EPHX1DPP4ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086131-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-13 | — | — | WO | disclosed |