Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884370 | 0.88 | CNR2 (0.43) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL15013956 | 0.85 | SCN9A (0.46) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL15008655 | 0.85 | TRPV6 (0.47) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL16884224 | 0.85 | SCN9A (0.45) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL16884198 | 0.82 | CNR2 (0.44) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL18088438 | 0.80 | HDAC6 (0.66) | HDAC6MEN1KMT2AHDAC8HDAC5 | |
| SCHEMBL16884189 | 0.79 | TRPV6 (0.45) | SCN9AHDAC6CNR2TRPV6LMNA | |
| SCHEMBL20237127 | 0.78 | HDAC6 (0.54) | SCN9AHDAC6TRPV6MEN1KMT2A | |
| SCHEMBL20236833 | 0.78 | HDAC6 (0.51) | SCN9AHDAC6CNR2LMNAMEN1 | |
| SCHEMBL31137114 | 0.76 | KDM1A (0.47) | HDAC6CTSDBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086131-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-13 | — | — | WO | disclosed |