Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280159 | 0.90 | ADORA2A (0.41) | IDO1METAP2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17279780 | 0.87 | MEN1 (0.43) | RAB9ANPC1SMN1; SMN2TSHRHPGD | |
| SCHEMBL28147150 | 0.86 | MAPT (0.42) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL29662878 | 0.86 | MAPK14 (0.53) | IDO1METAP2RAB9ANPC1XDH | |
| SCHEMBL26467067 | 0.85 | ACHE (0.48) | IDO1METAP2RAB9ANPC1XDH | |
| SCHEMBL31659868 | 0.85 | ACHE (0.48) | IDO1METAP2RAB9ANPC1XDH | |
| SCHEMBL17280165 | 0.84 | NR1H2 (0.44) | IDO1METAP2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7144815 | 0.84 | NR1H2 (0.51) | RAB9ANPC1SMN1; SMN2TSHRHPGD | |
| SCHEMBL7144979 | 0.84 | NR1H2 (0.51) | RAB9ANPC1SMN1; SMN2TSHRHPGD | |
| SCHEMBL528246 | 0.83 | MEN1 (0.46) | IDO1METAP2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846948-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8796467-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20130150355-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20130150347-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150347-A1 | NOVEL COMPOUNDS | GRM5, GRM1, GRIK5 | IDO1 3659/4885METAP2 3886/4885RAB9A 732/4885 |
| US-20130150355-A1 | NOVEL COMPOUNDS | GRM5, GRIN2A, GRIN1 | IDO1 3418/4885METAP2 4058/4885RAB9A 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.