SCHEMBL1502935

SCHEMBL1502935

C=Cc1ccc(S(=O)(=O)O)cc1S(=O)(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 5/20 0.40
SENP3 Q9H4L4 2/20 0.40
SENP2 Q9HC62 2/20 0.40
SENP1 Q9P0U3 2/20 0.40
SUMO2 P61956 1/20 0.40
SUMO1 P63165 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP6 P55212 1/20 0.40
RAD1 O60671 1/20 0.39
P2RY6 Q15077 1/20 0.39
LMNA P02545 2/20 0.39
TIMP3 P35625 1/20 0.38
TSHR P16473 4/20 0.38
NT5E P21589 2/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3714740 0.98 TDP1 (0.50) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL3789574 0.98 TDP1 (0.50) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL3719523 0.85 TDP1 (0.52) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL27894191 0.84 TDP1 (0.55) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL29396279 0.82 ALDH1A1 (0.41) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL225048 0.82 ALDH1A1 (0.41) TDP1ALDH1A1HSD17B10SENP3SENP2
SCHEMBL11964335 0.81 TDP1 (0.52) TDP1ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL1470769 0.81 TDP1 (0.52) TDP1ALDH1A1SENP3SENP2SENP1
SCHEMBL30757967 0.81 TDP1 (0.52) TDP1ALDH1A1SENP3SENP2SENP1
SCHEMBL2996002 0.81 ALDH1A1 (0.40) TDP1ALDH1A1HSD17B10SENP3SENP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022187813-A1 A DELTA-OPIOID RECEPTOR TARGETED AGENT FOR MOLECULAR IMAGING AND IMMUNOTHERAPY OF CANCER WEST VIRGINA UNIVERSITY BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIVERSITY (US) 2022-09-09 WO disclosed
US-10259899-B2 Vinylidene fluoride / 2,3,3,3-tetrafluoropropene copolymers ARKEMA INC. (US) 2019-04-16 US disclosed
US-9493595-B2 Vinylidene fluoride copolymers ARKEMA INC. (US) 2016-11-15 US disclosed
EP-2297213-B1 NOVEL VINYLIDENE FLUORIDE COPOLYMERS ARKEMA INC (US) 2012-11-07 EP disclosed
EP-2297214-B1 VINYLIDENE FLUORIDE / 2,3,3,3-TETRAFLUOROPROPENE COPOLYMERS ARKEMA INC (US) 2012-09-19 EP disclosed
US-20110111156-A1 NOVEL VINYLIDENE FLUORIDE COPOLYMERS ARKEMA INC. (US) 2011-05-12 US disclosed
US-20110097529-A1 VINYLIDENE FLUORIDE / 2,3,3,3-TETRAFLUOROPROPENE COPOLYMERS ARKEMA INC. (US) 2011-04-28 US disclosed
EP-2297213-A1 NOVEL VINYLIDENE FLUORIDE COPOLYMERS Arkema Inc. (US) 2011-03-23 EP disclosed
WO-2010135167-A1 COPOLYELECTROLYTE MONOMERS BEARING MULTIPLE ACID GROUPS ARKEMA INC. (US) 2010-11-25 WO disclosed
WO-2010005755-A1 NOVEL VINYLIDENE FLUORIDE COPOLYMERS ARKEMA INC. (US) 2010-01-14 WO disclosed
US-4294921-A Method of hardening gelatin FUJI PHOTO FILM CO., LTD. (JP) 1981-10-13 US disclosed
US-3992333-A NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER ROHM AND HAAS COMPANY (US) 1976-11-16 US disclosed
US-3980713-A FLUORESCENT BRIGHTENERS NIPPON KAYAKU CO., LTD. (JA) 1976-09-14 US disclosed