Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 7/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891411 | 0.88 | GRM2 (0.60) | GRM2 | |
| SCHEMBL6891879 | 0.88 | GRM2 (0.60) | GRM2 | |
| SCHEMBL6892790 | 0.88 | GRM2 (0.45) | GRM2MTNR1AMTNR1BDRD2EPHX2 | |
| SCHEMBL6893083 | 0.80 | GRM2 (0.59) | GRM2MTNR1AMTNR1B | |
| SCHEMBL1503036 | 0.79 | GRM2 (0.63) | GRM2 | |
| SCHEMBL1502995 | 0.79 | GRM2 (0.60) | GRM2 | |
| SCHEMBL1503058 | 0.78 | GRM2 (0.62) | GRM2 | |
| SCHEMBL6892275 | 0.78 | GRM2 (0.69) | GRM2PARG | |
| SCHEMBL1503086 | 0.77 | GRM2 (0.60) | GRM2MTNR1AMTNR1B | |
| SCHEMBL1502954 | 0.77 | GRM2 (0.60) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | claimed |
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |