⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241538 | 0.73 | — | — | |
| SCHEMBL8301298 | 0.71 | — | — | |
| SCHEMBL8301300 | 0.71 | — | — | |
| SCHEMBL11573273 | 0.67 | — | — | |
| SCHEMBL6903394 | 0.63 | — | — | |
| SCHEMBL975089 | 0.63 | — | — | |
| SCHEMBL4602390 | 0.63 | — | — | |
| SCHEMBL6085814 | 0.63 | — | — | |
| SCHEMBL15791946 | 0.63 | — | — | |
| SCHEMBL260946 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466163-B2 | Furo[2,3-d]pyrimidines and related compounds and methods for treating disease states by inhibiting tubulin polymerization | BIONOMICS LIMITED (AU) | 2013-06-18 | — | — | US | disclosed |