Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27812979 | 0.93 | MAOB (0.41) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| SCHEMBL30954800 | 0.81 | DAO (0.39) | MAOBNPC1MAPT | |
| SCHEMBL4304503 | 0.78 | PPARG (0.41) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| SCHEMBL1503267 | 0.76 | HDAC1 (0.41) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| SCHEMBL30954808 | 0.76 | HDAC1 (0.41) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| SCHEMBL2220322 | 0.75 | ALDH1A1 (0.40) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| Acetic Acid SCHEMBL27812972 | 0.75 | MAOB (0.43) | MAOBNPC1MAPT | |
| SCHEMBL22738223 | 0.74 | SCN9A (0.41) | MAOBNPC1MAPTMAPK1HSD17B10 | |
| SCHEMBL22738285 | 0.72 | MEN1 (0.40) | NPC1MAPTMAPK1HSD17B10SCN9A | |
| SCHEMBL22719900 | 0.72 | GRIN1 (0.40) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | claimed |