Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15424813 | 1.00 | CYP19A1 (0.33) | CYP19A1CA1CA2CA4MCHR1 | |
| SCHEMBL14018563 | 0.87 | CYP1A2 (0.35) | CYP19A1CYP1A2 | |
| SCHEMBL10151543 | 0.87 | CYP1A2 (0.35) | CYP19A1CYP1A2 | |
| SCHEMBL10160046 | 0.87 | CYP1A2 (0.35) | CYP19A1CYP1A2 | |
| SCHEMBL21357953 | 0.85 | KDM4E (0.34) | CA1CA2CA4KDM4ECYP1A2 | |
| SCHEMBL16656747 | 0.83 | SMN1; SMN2 (0.35) | CYP1A2 | |
| SCHEMBL14017758 | 0.83 | SMN1; SMN2 (0.35) | CYP1A2 | |
| SCHEMBL18102782 | 0.83 | SMN1; SMN2 (0.35) | CYP1A2 | |
| SCHEMBL17266376 | 0.83 | SMN1; SMN2 (0.35) | CYP1A2 | |
| SCHEMBL19055312 | 0.81 | ALDH1A1 (0.39) | CYP19A1CA1CA2CA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259284-A1 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME INTERNATIONAL SA (CH) | 2015-09-17 | — | — | US | disclosed |
| US-9006460-B2 | Process for preparing aminocyclohexyl ether compounds | CARDIOME INTERNATIONAL AG (CH) | 2015-04-14 | — | — | US | disclosed |
| US-20130149751-A1 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME INTERNATIONAL SA (CH) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259284-A1 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP3A43, CYP4B1, CYP3A4 | CYP19A1 74/4885CA1 2272/4885CA2 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.