Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042094 | 0.92 | HRH3 (0.38) | HRH3KCNH2NOTUMPDK2 | |
| SCHEMBL25042414 | 0.85 | MAPT (0.40) | ADRB1MAPTALDH1A1HRH3KCNH2 | |
| SCHEMBL9899784 | 0.84 | S100B (0.36) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9939965 | 0.81 | MAPT (0.36) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30279079 | 0.81 | CHRM3 (0.39) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25039395 | 0.81 | CHRM3 (0.39) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25042275 | 0.81 | HRH4 (0.39) | RAD52 | |
| SCHEMBL25187995 | 0.79 | GAA (0.54) | ADRB1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL16727173 | 0.79 | CCR1 (0.43) | ADRB1MAPTALDH1A1NOTUM | |
| SCHEMBL16181915 | 0.79 | NR1H2 (0.36) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |