Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899360 | 0.83 | MAPT (0.54) | MAPK1MAPTSMN1; SMN2GAAALDH3A1 | |
| SCHEMBL15033815 | 0.83 | MAPT (0.47) | MAPTCYP2D6RAB9ANPC1ALDH1A1 | |
| SCHEMBL16181921 | 0.82 | MAPK1 (0.47) | MAPK1MAPTSMN1; SMN2GAAALDH3A1 | |
| SCHEMBL9900549 | 0.77 | MAPT (0.66) | MAPK1MAPTSMN1; SMN2GAACYP2C9 | |
| SCHEMBL824836 | 0.76 | SMN1; SMN2 (0.50) | MAPK1MAPTSMN1; SMN2CYP2C9HTT | |
| SCHEMBL15033694 | 0.76 | ALDH1A1 (0.35) | MAPTHTTALDH1A1KDM4E | |
| SCHEMBL14271383 | 0.76 | MAPT (0.53) | MAPK1MAPTSMN1; SMN2GAACYP2C9 | |
| SCHEMBL21032108 | 0.75 | MAPT (0.47) | MAPK1MAPTSMN1; SMN2GAAHTT | |
| SCHEMBL12864867 | 0.71 | MAPT (0.64) | MAPK1MAPTSMN1; SMN2GAAALDH3A1 | |
| SCHEMBL171012 | 0.71 | MAPT (0.50) | MAPK1MAPTSMN1; SMN2GAAALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |