Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900024 | 0.88 | SCN10A (0.35) | SCN10AMEN1KMT2AUSP2GAA | |
| SCHEMBL25191149 | 0.84 | HSD17B10 (0.36) | SCN10AMEN1KMT2AUSP2GAA | |
| SCHEMBL14217240 | 0.82 | ALDH1A1 (0.36) | SCN10AMEN1KMT2AUSP2GAA | |
| SCHEMBL30279094 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AUSP2GAAALDH1A1 | |
| SCHEMBL25207396 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AUSP2GAAALDH1A1 | |
| SCHEMBL25199801 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AUSP2GAAALDH1A1 | |
| SCHEMBL31053484 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AUSP2GAAALDH1A1 | |
| SCHEMBL9899709 | 0.78 | SERPINE1 (0.47) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10036396 | 0.74 | MAPT (0.59) | MEN1KMT2AUSP2GAAALDH1A1 | |
| SCHEMBL25187995 | 0.74 | GAA (0.54) | MEN1KMT2AGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |