SCHEMBL15033964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15020320	0.93	MAPT (0.45)	MAPTALDH1A1USP2LMNAKMT2A
	SCHEMBL15033991	0.89	MAPT (0.43)	MAPTALDH1A1LMNAKMT2ASMN1; SMN2
	SCHEMBL13431373	0.89	TP53 (0.44)	MAPTALDH1A1USP2LMNAHDAC3
	SCHEMBL15033965	0.88	TSHR (0.47)	MAPTALDH1A1HDAC3HDAC4HDAC1
	SCHEMBL15033981	0.87	SMN1; SMN2 (0.54)	MAPTALDH1A1USP2LMNAKMT2A
	SCHEMBL15033945	0.83	MAPT (0.41)	MAPTALDH1A1USP2LMNAKMT2A
	SCHEMBL15033979	0.81	CETP (0.41)	MAPTALDH1A1USP2LMNAKMT2A
	SCHEMBL17591506	0.78	MAPT (0.42)	MAPTALDH1A1USP2LMNAKMT2A
	SCHEMBL314216	0.77	HDAC3 (0.60)	MAPTALDH1A1LMNAHDAC3HDAC4
	SCHEMBL314260	0.75	KMT2A (0.54)	MAPTALDH1A1LMNAKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.