Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27304878 | 0.98 | KMT2A (0.53) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL7408157 | 0.92 | KMT2A (0.50) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL572 | 0.85 | KMT2A (0.58) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL4686898 | 0.84 | LMNA (0.61) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL8085697 | 0.84 | CA12 (0.61) | KMT2AMAPTMEN1CASP3KDM4E | |
| SCHEMBL8585196 | 0.84 | ALDH1A1 (0.53) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL11515591 | 0.84 | TSHR (0.66) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL452462 | 0.83 | PLOD2 (0.56) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL1739390 | 0.83 | ALDH1A1 (0.56) | KMT2AMAPTMEN1CASP3TRPV1 | |
| SCHEMBL11548787 | 0.83 | MAPT (0.45) | KMT2AMAPTMEN1CASP3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072476-B | Method for high-selectivity fluoromethylation of beta-keto ester compounds on oxygen | 南京理工大学 | 2022-10-21 | — | — | CN | claimed |
| CN-112778133-A | high-pH-value chrome tanning auxiliary agent containing polyfunctional group structure and preparation method and application thereof | 南京工业大学 | 2021-05-11 | — | — | CN | claimed |
| CN-111072476-A | β -ketoester compound oxygen high-selectivity monofluoromethylation method | 南京理工大学 | 2020-04-28 | — | — | CN | claimed |
| CN-106831603-B | A kind of preparation method containing fluoropyrimidine compound | 辽宁大学 | 2019-07-02 | — | — | CN | claimed |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2026-03-12 | — | — | US | disclosed |
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| EP-3525785-B1 | KDM5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-08-27 | — | — | EP | disclosed |
| EP-4580620-A2 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS, COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | Hager Biosciences, LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| EP-4577205-A2 | SUBSTITUTED PYRAZOLES AND IMIDAZOLES AS OREXIN RECEPTOR ANTAGONISTS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | Hager Biosciences, LLC (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-118619800-A | Amino dithioformate compound and preparation method thereof | 抚州三和医药化工有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118598836-A | Method for asymmetrically synthesizing chiral trans-3, 4-dihydrocoumarin derivative | 中北大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-118271261-A | Dicarbonyl compound containing cyclobutane segment and synthesis method thereof | 中国科学技术大学 | 2024-07-02 | — | — | CN | disclosed |
| EP-0027018-B1 | PROCESS FOR THE PRODUCTION OF 2-CHLORO-4-SUBSTITUTED-5-THIAZOLECARBOXYLATES | MONSANTO COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
| EP-0029915-B1 | DEVICE AND METHOD FOR THE PREPARATION OF A CONTROL SOLUTION FOR KETONE DETERMINATION AND METHOD OF CALIBRATING A KETONE TEST INSTRUMENT | MILES LABORATORIES, INC. (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| EP-0051209-A1 | Device and method for preparation of a control solution for ketone determination | MILES LABORATORIES, INC. (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4316737-A | PREEMERGENCE HERBICIDES | PHILAGRO (FR) | 1982-02-23 | — | — | US | disclosed |
| US-4308391-A | 2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives | MONSANTO COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0029915-A1 | Device and method for the preparation of a control solution for ketone determination and method of calibrating a ketone test instrument | MILES LABORATORIES, INC. (US) | 1981-06-10 | — | — | EP | disclosed |
| EP-0027018-A1 | Process for the production of 2-chloro-4-substituted-5-thiazolecarboxylates | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | POLRMT, TFAM, POLM | KMT2A 562/4885MAPT 716/4885MEN1 3371/4885 |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | OPRK1, OPRD1, HCRTR2 | KMT2A 1361/4885MAPT 787/4885MEN1 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.