Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025841 | 0.87 | GPR119 (0.44) | GPR119HTTPTPN2PTPN1PTPN6 | |
| SCHEMBL17715352 | 0.87 | GPR119 (0.44) | GPR119HTTPTPN2PTPN1PTPN6 | |
| SCHEMBL9937289 | 0.87 | GPR119 (0.58) | GPR119 | |
| SCHEMBL9937286 | 0.87 | GPR119 (0.58) | GPR119 | |
| SCHEMBL14244872 | 0.87 | GPR119 (0.58) | GPR119 | |
| SCHEMBL17011386 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL9974243 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL15366813 | 0.81 | GPR119 (0.43) | GPR119 | |
| SCHEMBL9936587 | 0.81 | GPR119 (0.40) | GPR119 | |
| SCHEMBL9936330 | 0.81 | GPR119 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083775-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |