Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
| ▸ | GAPDH | P04406 | 2/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503551 | 1.00 | TRPA1 (0.48) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1785095 | 0.94 | TRPA1 (0.56) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1785098 | 0.94 | TRPA1 (0.56) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1784815 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1780871 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1786457 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1782362 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1783802 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1783803 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 | |
| SCHEMBL1784813 | 0.92 | TRPA1 (0.55) | TRPA1GAPDHDDAH1MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477636-B1 | Tolerogenic dendritic cells for the treatment and prevention of atherosclerosis | CardioVax LLC (US) | 2015-05-06 | — | — | EP | claimed |
| US-20170100432-A1 | ANTIGEN SPECIFIC TOLEROGENIC ANTIGEN PRESENTING CELLS AND RELATED USES COMPOSITIONS, METHODS AND SYSTEMS | CARDIOVAX, LLC (US) | 2017-04-13 | — | — | US | disclosed |
| EP-2477636-B1 | Tolerogenic dendritic cells for the treatment and prevention of atherosclerosis | CardioVax LLC (US) | 2015-05-06 | — | — | EP | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120251513-A1 | Antigen Specific Tolerogenic Antigen Presenting Cells and Related Uses Compositions, Methods and Systems | CARDIOVAX, LLC | 2012-10-04 | — | — | US | disclosed |
| EP-2477636-A1 | ANTIGEN SPECIFIC TOLEROGENIC ANTIGEN PRESENTING CELLS AND RELATED USES COMPOSITIONS, METHODS AND SYSTEMS | Forskarpatent I SYD AB (SE) | 2012-07-25 | — | — | EP | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2011033090-A1 | ANTIGEN SPECIFIC TOLEROGENIC ANTIGEN PRESENTING CELLS AND RELATED USES COMPOSITIONS, METHODS AND SYSTEMS | FORSKARPATENT I SYD AB (SE) | 2011-03-24 | — | — | WO | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | TRPA1 1/4885GAPDH 3057/4885DDAH1 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.