Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15036646 | 1.00 | KCNJ1 (0.69) | KCNJ1KCNH2 | |
| SCHEMBL15036773 | 0.92 | KCNJ1 (0.70) | KCNJ1KCNH2 | |
| SCHEMBL15036645 | 0.85 | KCNJ1 (0.66) | KCNJ1KCNH2 | |
| SCHEMBL15036650 | 0.85 | KCNJ1 (0.66) | KCNJ1KCNH2 | |
| SCHEMBL15036643 | 0.82 | KCNJ1 (0.66) | KCNJ1KCNH2 | |
| SCHEMBL15036956 | 0.82 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL15036965 | 0.81 | KCNJ1 (0.54) | KCNJ1KCNH2 | |
| SCHEMBL16227663 | 0.80 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL16227496 | 0.80 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL16227699 | 0.80 | KCNJ1 (1.00) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090271-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-06-20 | — | — | WO | disclosed |