Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957064 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL1468542 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL6309026 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL25404144 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL21027289 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL25406757 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL6308014 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL873713 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL11795363 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA | |
| SCHEMBL6308012 | 1.00 | MAPT (0.68) | MAPTALDH1A1FAAHPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007173-B2 | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2021-05-18 | — | — | US | disclosed |
| US-20200093790-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | AMARIN CORPORATION PLC. (IE) | 2020-03-26 | — | — | US | disclosed |
| US-10493058-B2 | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2019-12-03 | — | — | US | disclosed |
| US-20150265574-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2015-09-24 | — | — | US | disclosed |
| EP-2480248-B1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | AMARIN PHARMACEUTICALS IE LTD (IE) | 2015-09-02 | — | — | EP | disclosed |
| US-20140080850-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN OMEGA-3 FATTY ACID AND A HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2014-03-20 | — | — | US | disclosed |
| US-20110071176-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | AMARIN PHARMA, INC. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265574-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | HMGCR, ELOVL3, SCD | MAPT 3104/4885ALDH1A1 1417/4885FAAH 247/4885 |
| US-20140080850-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN OMEGA-3 FATTY ACID AND A HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | HMGCR, ELOVL3, FABP3 | MAPT 3343/4885ALDH1A1 1492/4885FAAH 202/4885 |
| US-20200093790-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | HMGCR, ELOVL3, SCD | MAPT 3104/4885ALDH1A1 1417/4885FAAH 247/4885 |
| US-10493058-B2 | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same | HMGCR, ELOVL3, SCD | MAPT 3104/4885ALDH1A1 1417/4885FAAH 247/4885 |
| US-11007173-B2 | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same | HMGCR, ELOVL3, SCD | MAPT 3104/4885ALDH1A1 1417/4885FAAH 247/4885 |
| US-20110071176-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME | HMGCR, ELOVL3, SCD | MAPT 3104/4885ALDH1A1 1417/4885FAAH 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.