Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL11263308 | 0.88 | ALDH1A1 (0.52) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL2316524 | 0.84 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Benzene SCHEMBL28254104 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL30259301 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL31100 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Styrene SCHEMBL28935148 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Hydrochloric Acid SCHEMBL2909959 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL347539 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Ammonia Solution, Strong SCHEMBL6551345 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL2867924 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011116939-A | CURING AGENT FOR EPOXY RESIN | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 2011-06-16 | — | — | JP | disclosed |
| WO-2011025040-A1 | CURING AGENT FOR EPOXY RESINS | 日本合成化学工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |
| EP-0544819-B1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | ABBOTT LAB (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5459150-A | Treatment of allergies and inflammatory diseases | ABBOTT LABORATORIES (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0544819-A4 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0544819-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5095031-A | Enzyme inhibitors, antiallergens, antiinflammatory | ABBOTT LABORATORIES (US) | 1992-03-10 | — | — | US | disclosed |
| WO-1992003132-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |