Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019649 | 0.93 | PLG (0.49) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL15037417 | 0.93 | PLG (0.49) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL15037348 | 0.93 | PLG (0.49) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL15019646 | 0.93 | PLG (0.49) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL22384176 | 0.92 | PLG (0.48) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL16305936 | 0.91 | KLKB1 (0.44) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL15019724 | 0.90 | PPARG (0.47) | PLGKLKB1PPARGPPARAITGB3 | |
| SCHEMBL15019658 | 0.90 | PPARG (0.47) | PLGKLKB1PPARGPPARAITGB3 | |
| SCHEMBL16306210 | 0.90 | PLG (0.47) | PLGKLKB1L3MBTL1PPARGPPARA | |
| SCHEMBL19807191 | 0.90 | PLG (0.49) | PLGKLKB1L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090454-A2 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |