Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019649 | 0.92 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL15019646 | 0.92 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL15037417 | 0.92 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL15037348 | 0.92 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL15037414 | 0.92 | PLG (0.51) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL16306210 | 0.89 | PLG (0.47) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL19807191 | 0.89 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL19807189 | 0.89 | PLG (0.49) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL17834391 | 0.89 | PLG (0.47) | PLGL3MBTL1KLKB1PPARGPPARA | |
| SCHEMBL16295907 | 0.89 | PPARG (0.45) | PLGL3MBTL1KLKB1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |